| Issue |
RAIRO-Theor. Inf. Appl.
Volume 45, Number 1, January-March 2011
ICTCS 09
|
|
|---|---|---|
| Page(s) | 35 - 58 | |
| DOI | https://doi.org/10.1051/ita/2011010 | |
| Published online | 15 March 2011 | |
Enumerated type semantics for the calculus of looping sequences
Dipartimento di Informatica, Università
di Torino, Torino, Italy; biogliol@di.unito.it
Received:
22
February
2010
Accepted:
18
November
2010
The calculus of looping sequences is a formalism for describing the evolution of biological systems by means of term rewriting rules. In this paper we enrich this calculus with a type discipline which preserves some biological properties depending on the minimum and the maximum number of elements of some type requested by the present elements. The type system enforces these properties and typed reductions guarantee that evolution preserves them. As an example, we model the hemoglobin structure and the equilibrium between cell death and division: typed reductions prevent undesirable behaviors.
Mathematics Subject Classification: 03B15 / 68Q42 / 68Q55 / 68Q65 / 92C42
Key words: System biology / predictive modelling / CLS / type systems
© EDP Sciences, 2011
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